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Jurgen Corthals Selected Research

trimix

1/2020TriMix and tumor antigen mRNA electroporated dendritic cell vaccination plus ipilimumab: link between T-cell activation and clinical responses in advanced melanoma.
9/2014Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula.
7/2012Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient.
6/2011Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma.
5/2009Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.

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Jurgen Corthals Research Topics

Disease

23Neoplasms (Cancer)
12/2020 - 06/2002
16Melanoma (Melanoma, Malignant)
12/2020 - 07/2003
2Multiple Myeloma
04/2018 - 10/2014
2Neoplasm Metastasis (Metastasis)
03/2015 - 06/2011
2Human Influenza (Influenza)
09/2003 - 06/2002
1Breast Neoplasms (Breast Cancer)
06/2019
1Wilms Tumor (Wilm's Tumor)
11/2013
1Injection Site Reaction
06/2011
1Fever (Fevers)
06/2011
1Delayed Hypersensitivity (Hypersensitivity, Type IV)
06/2011
1HIV Infections (HIV Infection)
06/2011
1Lethargy
06/2011
1Communicable Diseases (Infectious Diseases)
06/2002

Drug/Important Bio-Agent (IBA)

14Messenger RNA (mRNA)IBA
12/2020 - 06/2002
11AntigensIBA
01/2020 - 10/2007
9VaccinesIBA
08/2019 - 06/2002
6Neoplasm Antigens (Tumor Antigens)IBA
01/2020 - 01/2008
6Proteins (Proteins, Gene)FDA Link
04/2016 - 06/2002
5trimixIBA
01/2020 - 05/2009
4Monophenol Monooxygenase (Tyrosinase)IBA
01/2020 - 05/2009
3IpilimumabIBA
01/2020 - 04/2011
3Monoclonal AntibodiesIBA
06/2019 - 04/2011
2CD40 Ligand (CD40L)IBA
12/2020 - 01/2020
2Lenalidomide (CC 5013)FDA Link
04/2018 - 10/2014
2MART-1 AntigenIBA
01/2008 - 09/2003
1Formaldehyde (Formol)FDA Link
12/2020
1ParaffinIBA
12/2020
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
06/2019
1Immunoglobulins (Immunoglobulin)IBA
04/2016
1SolutionsIBA
01/2016
1Interferon alpha-2 (Roferon-A)FDA Link
03/2015
1pomalidomideIBA
10/2014
1Immunomodulating AgentsIBA
10/2014
1N-acetyltalosaminuronic acid (NAT)IBA
09/2014
1AZD 1480IBA
08/2014
1Pharmaceutical PreparationsIBA
08/2014
1Phosphotransferases (Kinase)IBA
08/2014
1WT1 ProteinsIBA
11/2013
1Dacarbazine (DIC)FDA LinkGeneric
07/2012
1Protein Sorting Signals (Signal Peptide)IBA
05/2012
1EpitopesIBA
05/2012
1CytokinesIBA
06/2011
1HLA Antigens (Human Leukocyte Antigens)IBA
06/2011
1CTLA-4 AntigenIBA
04/2011
1InterferonsIBA
04/2011
1HLA-DR1 Antigen (HLA DR1 Antigen)IBA
07/2003
1Peptides (Polypeptides)IBA
07/2003
1Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA
07/2003
1Dextrans (Dextran)FDA Link
06/2002

Therapy/Procedure

9Immunotherapy
01/2016 - 09/2003
3Therapeutics
03/2015 - 06/2011
2Intravenous Injections
06/2019 - 07/2012
2Stem Cell Transplantation
04/2018 - 10/2014
1Drug Therapy (Chemotherapy)
07/2012
1Injections
07/2012
1Microspheres (Microsphere)
06/2002